Systematic review and meta-analysis

– Introduction
– Methods
• search strategy : PubMed, Cochran, Embase
• inclusion and exclusion
criteria
• data extraction and bias
assessment
• outcomes of interest
• statistical analysis (can use RevMan V.5.4 or other)
– Result
• search results (include PRISMA flow diagram)
• study characteristics (include table)
• risk of bias in included studies
• meta-analysis results
(1) change in BCVA
(2) improvement of 15 or more ETDRS letters
(3) central retinal thickness （OCT)
(4) loss of 15 or more ETDRS letters
(5) quality of life
(6) adverse event and complication
(7) subgroup analysis results
(8) sensitivity analysis
– Discussion
– Conclusion