I have attached my paper with corrections and would like for you to please fix m

April 27, 2024

I have attached my paper with corrections and would like for you to please fix my paper 
according to those corrections. The title on my paper is NO longer the title so DISREGARD 
that please! 
“Neuroprotective Potential of Phytochemicals from Selected Plant and Fungal sources in
Alzheimer’s Disease”    – new title 
Also, I know that the objectives, materials and methodolgy, results, and discussion may be difficult, but it would be greatly appreciated if you could do that part to the best of your 
ability. I will attach everything I think you will need to better 
understand my project and please do not hesitate to ask questions!
I have attached my ABSTRACT.  There is a part of my paper where my
profesor instructed me to MODIFY so that it correlates to my abstract!
LASTLY, to further help with the objectives, methodology and results I will attach some info 
below 
OBJECTIVES 
-Currently, there is no cure for AD, and available treatments only address symptoms. So Identifying phytochemicals that can protect against neurodegeneration may lead to the development of new treatment options that can slow down or halt the progression of the disease.
-Phytochemicals, natural compounds hav fewer side effects compared to synthetic drugs. If effective, phytochemical-based treatments could offer a safer alternative for AD patients.
-Plant and fungal sources are more affordable and accessible compared to synthetic drugs. This could make potential treatments more widely available to those who need them.
-AD is very complex and complicated, with increasing prevalence as the populations age. 
Overall, research on testing the phenolic content in specific plant samples has the potential to offer new hope for patients, caregivers, and healthcare providers.
MY RESEARCH / MATERIALS & METHODOLOGY 
Within my research we are testing natural products (Tumeric, Lions Mane, Green Tea, Sea 
moss and hemp) for its Neuroprotective Potential to aid in the advancement of AD.
– Tumeric and – green tea have proven benefits in the improvement of memory and 
cognitive function The two antioxidants present epigallocatechin gallate (EGCG)  from green tea and curcumin in turmeric have been investigated for their potential therapeutic effects 
in AD. Curcumin for its anti-inflammatory, antioxidant, and neuroprotective properties. And 
egcg for for its potential to protect brain cells from damage and improve memory and cognition.
– Lions mane – Promising results that were done in preclinical studies, but the
results have not been replicated.  Preclinical studies have shown that lion’s mane appears to
protect against oxidative stress – The brain is more vulnerable than other organs to 
oxidative stress, … Oxidative stress participates in the development of AD
– Hemp has shown to have efficient anti-neuroinflammatory activity, which without 
could lead to the tangles 
– Sea moss, type of seaweed that is rich in nutrients such as iodine, potassium, and 
magnesium.
high nutrient content and potential anti-inflammatory properties, 
no scientific evidence to support this claim. 
Research imited 
WHAT DID I DO IN THE LAB?
SEE ATTACHED “MATERIALS AND PROCEDURE”
to sum it up… 
– EXTRACTION
Collected plant samples 
Grinded them
Extracted the plant tissues in 80% methanol
Vortex those samples for an effective mix of samples
Sonicate 15 min , 40 degree celsius (agitate the particles in the sample through sonifictaion)
Centrifuge and collected the supernatant
Filtered to remove any unwanted debris
Kept it at 80 degree celsius 
– QUANTIFICATIONS 
SEE ATTACHED PAPER FOR THE 3 QUANTIFICATIONS PERFORMED.
I think all of this will help for a graet paper. Please let me know if more is needed. 
ACS STYLE REFERENCES 

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